diff --git a/src/test/regress/expected/isolation_multiuser_locking.out b/src/test/regress/expected/isolation_multiuser_locking.out
index a667b5dfb..30f474b84 100644
--- a/src/test/regress/expected/isolation_multiuser_locking.out
+++ b/src/test/regress/expected/isolation_multiuser_locking.out
@@ -2,295 +2,337 @@ Parsed test spec with 2 sessions
 
 starting permutation: s1-begin s2-begin s2-reindex s1-insert s2-commit s1-commit
 step s1-begin:
- BEGIN;
- SET ROLE test_user_1;
+	BEGIN;
+	SET ROLE test_user_1;
 
 step s2-begin:
- BEGIN;
- SET ROLE test_user_2;
+	BEGIN;
+	SET ROLE test_user_2;
 
 step s2-reindex:
- REINDEX TABLE test_table;
+	REINDEX TABLE test_table;
 
 ERROR:  must be owner of table test_table
 step s1-insert:
- UPDATE test_table SET column2 = 1;
+	UPDATE test_table SET column2 = 1;
 
 step s2-commit:
- COMMIT;
+	COMMIT;
 
 step s1-commit:
- COMMIT;
+	COMMIT;
 
 
 starting permutation: s1-grant s1-begin s2-begin s2-reindex s1-insert s2-insert s2-commit s1-commit
 step s1-grant:
- SET ROLE test_user_1;
- SELECT bool_and(success) FROM run_command_on_placements('test_table', 'GRANT ALL ON TABLE %s TO test_user_2');
- GRANT ALL ON test_table TO test_user_2;
+	SET ROLE test_user_1;
+	SELECT bool_and(success) FROM run_command_on_placements('test_table', 'GRANT ALL ON TABLE %s TO test_user_2');
+	GRANT ALL ON test_table TO test_user_2;
+	SELECT run_command_on_workers($$SET citus.enable_metadata_sync TO off; GRANT ALL ON test_table TO test_user_2;$$);
 
 bool_and
 ---------------------------------------------------------------------
 t
 (1 row)
 
+run_command_on_workers
+---------------------------------------------------------------------
+(localhost,57637,t,SET)
+(localhost,57638,t,SET)
+(2 rows)
+
 step s1-begin:
- BEGIN;
- SET ROLE test_user_1;
+	BEGIN;
+	SET ROLE test_user_1;
 
 step s2-begin:
- BEGIN;
- SET ROLE test_user_2;
+	BEGIN;
+	SET ROLE test_user_2;
 
 step s2-reindex:
- REINDEX TABLE test_table;
+	REINDEX TABLE test_table;
 
 ERROR:  must be owner of table test_table
 step s1-insert:
- UPDATE test_table SET column2 = 1;
+	UPDATE test_table SET column2 = 1;
 
 step s2-insert:
- UPDATE test_table SET column2 = 2;
+	UPDATE test_table SET column2 = 2;
 
 ERROR:  current transaction is aborted, commands ignored until end of transaction block
 step s2-commit:
- COMMIT;
+	COMMIT;
 
 step s1-commit:
- COMMIT;
+	COMMIT;
 
 
 starting permutation: s1-grant s1-begin s2-begin s1-reindex s2-insert s1-insert s1-commit s2-commit
 step s1-grant:
- SET ROLE test_user_1;
- SELECT bool_and(success) FROM run_command_on_placements('test_table', 'GRANT ALL ON TABLE %s TO test_user_2');
- GRANT ALL ON test_table TO test_user_2;
+	SET ROLE test_user_1;
+	SELECT bool_and(success) FROM run_command_on_placements('test_table', 'GRANT ALL ON TABLE %s TO test_user_2');
+	GRANT ALL ON test_table TO test_user_2;
+	SELECT run_command_on_workers($$SET citus.enable_metadata_sync TO off; GRANT ALL ON test_table TO test_user_2;$$);
 
 bool_and
 ---------------------------------------------------------------------
 t
 (1 row)
 
+run_command_on_workers
+---------------------------------------------------------------------
+(localhost,57637,t,SET)
+(localhost,57638,t,SET)
+(2 rows)
+
 step s1-begin:
- BEGIN;
- SET ROLE test_user_1;
+	BEGIN;
+	SET ROLE test_user_1;
 
 step s2-begin:
- BEGIN;
- SET ROLE test_user_2;
+	BEGIN;
+	SET ROLE test_user_2;
 
 step s1-reindex:
- REINDEX TABLE test_table;
+	REINDEX TABLE test_table;
 
 step s2-insert:
- UPDATE test_table SET column2 = 2;
+	UPDATE test_table SET column2 = 2;
  <waiting ...>
 step s1-insert: 
- UPDATE test_table SET column2 = 1;
+	UPDATE test_table SET column2 = 1;
 
 step s1-commit:
- COMMIT;
+	COMMIT;
 
 step s2-insert: <... completed>
 step s2-commit:
- COMMIT;
+	COMMIT;
 
 
 starting permutation: s1-begin s2-begin s2-index s1-insert s2-commit s1-commit s2-drop-index
 step s1-begin:
- BEGIN;
- SET ROLE test_user_1;
+	BEGIN;
+	SET ROLE test_user_1;
 
 step s2-begin:
- BEGIN;
- SET ROLE test_user_2;
+	BEGIN;
+	SET ROLE test_user_2;
 
 step s2-index:
- CREATE INDEX test_index ON test_table(column1);
+	CREATE INDEX test_index ON test_table(column1);
 
 ERROR:  must be owner of table test_table
 step s1-insert:
- UPDATE test_table SET column2 = 1;
+	UPDATE test_table SET column2 = 1;
 
 step s2-commit:
- COMMIT;
+	COMMIT;
 
 step s1-commit:
- COMMIT;
+	COMMIT;
 
 step s2-drop-index:
- DROP INDEX IF EXISTS test_index;
+	DROP INDEX IF EXISTS test_index;
 
 
 starting permutation: s1-grant s1-begin s2-begin s2-insert s1-index s2-insert s2-commit s1-commit s1-drop-index
 step s1-grant:
- SET ROLE test_user_1;
- SELECT bool_and(success) FROM run_command_on_placements('test_table', 'GRANT ALL ON TABLE %s TO test_user_2');
- GRANT ALL ON test_table TO test_user_2;
+	SET ROLE test_user_1;
+	SELECT bool_and(success) FROM run_command_on_placements('test_table', 'GRANT ALL ON TABLE %s TO test_user_2');
+	GRANT ALL ON test_table TO test_user_2;
+	SELECT run_command_on_workers($$SET citus.enable_metadata_sync TO off; GRANT ALL ON test_table TO test_user_2;$$);
 
 bool_and
 ---------------------------------------------------------------------
 t
 (1 row)
 
+run_command_on_workers
+---------------------------------------------------------------------
+(localhost,57637,t,SET)
+(localhost,57638,t,SET)
+(2 rows)
+
 step s1-begin:
- BEGIN;
- SET ROLE test_user_1;
+	BEGIN;
+	SET ROLE test_user_1;
 
 step s2-begin:
- BEGIN;
- SET ROLE test_user_2;
+	BEGIN;
+	SET ROLE test_user_2;
 
 step s2-insert:
- UPDATE test_table SET column2 = 2;
+	UPDATE test_table SET column2 = 2;
 
 step s1-index:
- CREATE INDEX test_index ON test_table(column1);
+	CREATE INDEX test_index ON test_table(column1);
  <waiting ...>
 step s2-insert: 
- UPDATE test_table SET column2 = 2;
+	UPDATE test_table SET column2 = 2;
 
 step s2-commit:
- COMMIT;
+	COMMIT;
 
 step s1-index: <... completed>
 step s1-commit:
- COMMIT;
+	COMMIT;
 
 step s1-drop-index:
- DROP INDEX IF EXISTS test_index;
+	DROP INDEX IF EXISTS test_index;
 
 
 starting permutation: s1-grant s1-begin s2-begin s1-index s2-index s1-insert s1-commit s2-commit s1-drop-index s2-drop-index
 step s1-grant:
- SET ROLE test_user_1;
- SELECT bool_and(success) FROM run_command_on_placements('test_table', 'GRANT ALL ON TABLE %s TO test_user_2');
- GRANT ALL ON test_table TO test_user_2;
+	SET ROLE test_user_1;
+	SELECT bool_and(success) FROM run_command_on_placements('test_table', 'GRANT ALL ON TABLE %s TO test_user_2');
+	GRANT ALL ON test_table TO test_user_2;
+	SELECT run_command_on_workers($$SET citus.enable_metadata_sync TO off; GRANT ALL ON test_table TO test_user_2;$$);
 
 bool_and
 ---------------------------------------------------------------------
 t
 (1 row)
 
+run_command_on_workers
+---------------------------------------------------------------------
+(localhost,57637,t,SET)
+(localhost,57638,t,SET)
+(2 rows)
+
 step s1-begin:
- BEGIN;
- SET ROLE test_user_1;
+	BEGIN;
+	SET ROLE test_user_1;
 
 step s2-begin:
- BEGIN;
- SET ROLE test_user_2;
+	BEGIN;
+	SET ROLE test_user_2;
 
 step s1-index:
- CREATE INDEX test_index ON test_table(column1);
+	CREATE INDEX test_index ON test_table(column1);
 
 step s2-index:
- CREATE INDEX test_index ON test_table(column1);
+	CREATE INDEX test_index ON test_table(column1);
 
 ERROR:  must be owner of table test_table
 step s1-insert:
- UPDATE test_table SET column2 = 1;
+	UPDATE test_table SET column2 = 1;
 
 step s1-commit:
- COMMIT;
+	COMMIT;
 
 step s2-commit:
- COMMIT;
+	COMMIT;
 
 step s1-drop-index:
- DROP INDEX IF EXISTS test_index;
+	DROP INDEX IF EXISTS test_index;
 
 step s2-drop-index:
- DROP INDEX IF EXISTS test_index;
+	DROP INDEX IF EXISTS test_index;
 
 
 starting permutation: s1-begin s2-begin s2-truncate s1-insert s2-commit s1-commit
 step s1-begin:
- BEGIN;
- SET ROLE test_user_1;
+	BEGIN;
+	SET ROLE test_user_1;
 
 step s2-begin:
- BEGIN;
- SET ROLE test_user_2;
+	BEGIN;
+	SET ROLE test_user_2;
 
 step s2-truncate:
- TRUNCATE test_table;
+	TRUNCATE test_table;
 
 ERROR:  permission denied for table test_table
 step s1-insert:
- UPDATE test_table SET column2 = 1;
+	UPDATE test_table SET column2 = 1;
 
 step s2-commit:
- COMMIT;
+	COMMIT;
 
 step s1-commit:
- COMMIT;
+	COMMIT;
 
 
 starting permutation: s1-grant s1-begin s2-begin s1-truncate s2-insert s1-insert s1-commit s2-commit
 step s1-grant:
- SET ROLE test_user_1;
- SELECT bool_and(success) FROM run_command_on_placements('test_table', 'GRANT ALL ON TABLE %s TO test_user_2');
- GRANT ALL ON test_table TO test_user_2;
+	SET ROLE test_user_1;
+	SELECT bool_and(success) FROM run_command_on_placements('test_table', 'GRANT ALL ON TABLE %s TO test_user_2');
+	GRANT ALL ON test_table TO test_user_2;
+	SELECT run_command_on_workers($$SET citus.enable_metadata_sync TO off; GRANT ALL ON test_table TO test_user_2;$$);
 
 bool_and
 ---------------------------------------------------------------------
 t
 (1 row)
 
+run_command_on_workers
+---------------------------------------------------------------------
+(localhost,57637,t,SET)
+(localhost,57638,t,SET)
+(2 rows)
+
 step s1-begin:
- BEGIN;
- SET ROLE test_user_1;
+	BEGIN;
+	SET ROLE test_user_1;
 
 step s2-begin:
- BEGIN;
- SET ROLE test_user_2;
+	BEGIN;
+	SET ROLE test_user_2;
 
 step s1-truncate:
- TRUNCATE test_table;
+	TRUNCATE test_table;
 
 step s2-insert:
- UPDATE test_table SET column2 = 2;
+	UPDATE test_table SET column2 = 2;
  <waiting ...>
 step s1-insert: 
- UPDATE test_table SET column2 = 1;
+	UPDATE test_table SET column2 = 1;
 
 step s1-commit:
- COMMIT;
+	COMMIT;
 
 step s2-insert: <... completed>
 step s2-commit:
- COMMIT;
+	COMMIT;
 
 
 starting permutation: s1-grant s1-begin s2-begin s1-truncate s2-truncate s1-commit s2-commit
 step s1-grant:
- SET ROLE test_user_1;
- SELECT bool_and(success) FROM run_command_on_placements('test_table', 'GRANT ALL ON TABLE %s TO test_user_2');
- GRANT ALL ON test_table TO test_user_2;
+	SET ROLE test_user_1;
+	SELECT bool_and(success) FROM run_command_on_placements('test_table', 'GRANT ALL ON TABLE %s TO test_user_2');
+	GRANT ALL ON test_table TO test_user_2;
+	SELECT run_command_on_workers($$SET citus.enable_metadata_sync TO off; GRANT ALL ON test_table TO test_user_2;$$);
 
 bool_and
 ---------------------------------------------------------------------
 t
 (1 row)
 
+run_command_on_workers
+---------------------------------------------------------------------
+(localhost,57637,t,SET)
+(localhost,57638,t,SET)
+(2 rows)
+
 step s1-begin:
- BEGIN;
- SET ROLE test_user_1;
+	BEGIN;
+	SET ROLE test_user_1;
 
 step s2-begin:
- BEGIN;
- SET ROLE test_user_2;
+	BEGIN;
+	SET ROLE test_user_2;
 
 step s1-truncate:
- TRUNCATE test_table;
+	TRUNCATE test_table;
 
 step s2-truncate:
- TRUNCATE test_table;
+	TRUNCATE test_table;
  <waiting ...>
 step s1-commit: 
- COMMIT;
+	COMMIT;
 
 step s2-truncate: <... completed>
 step s2-commit:
- COMMIT;
+	COMMIT;
 
diff --git a/src/test/regress/expected/isolation_replicate_reference_tables_to_coordinator.out b/src/test/regress/expected/isolation_replicate_reference_tables_to_coordinator.out
index d28a6b714..c012ef156 100644
--- a/src/test/regress/expected/isolation_replicate_reference_tables_to_coordinator.out
+++ b/src/test/regress/expected/isolation_replicate_reference_tables_to_coordinator.out
@@ -103,8 +103,8 @@ step s2-view-worker:
 
 query                                                                         |query_hostname  |query_hostport|distributed_query_host_name|distributed_query_host_port|state              |wait_event_type|wait_event|usename |datname
 ---------------------------------------------------------------------
-UPDATE public.ref_table_1500767 ref_table SET a = (a OPERATOR(pg_catalog.+) 1)|localhost     |         57638|coordinator_host           |                      57636|idle in transaction|Client         |ClientRead|postgres|regression
-UPDATE public.ref_table_1500767 ref_table SET a = (a OPERATOR(pg_catalog.+) 1)|localhost     |         57637|coordinator_host           |                      57636|idle in transaction|Client         |ClientRead|postgres|regression
+UPDATE public.ref_table_1500803 ref_table SET a = (a OPERATOR(pg_catalog.+) 1)|localhost     |         57638|coordinator_host           |                      57636|idle in transaction|Client         |ClientRead|postgres|regression
+UPDATE public.ref_table_1500803 ref_table SET a = (a OPERATOR(pg_catalog.+) 1)|localhost     |         57637|coordinator_host           |                      57636|idle in transaction|Client         |ClientRead|postgres|regression
 (2 rows)
 
 step s2-end:
diff --git a/src/test/regress/isolation_schedule b/src/test/regress/isolation_schedule
index a2583034a..6108d3542 100644
--- a/src/test/regress/isolation_schedule
+++ b/src/test/regress/isolation_schedule
@@ -89,6 +89,7 @@ test: isolation_ref_update_delete_upsert_vs_all_on_mx
 test: isolation_dis2ref_foreign_keys_on_mx
 test: isolation_metadata_sync_deadlock
 test: isolation_replicated_dist_on_mx
+test: isolation_multiuser_locking
 
 # MXless tests
 test: isolation_check_mx
@@ -96,4 +97,3 @@ test: isolation_replicate_reference_tables_to_coordinator
 test: isolation_turn_mx_off
 test: isolation_reference_copy_vs_all
 test: isolation_ref2ref_foreign_keys
-test: isolation_multiuser_locking
diff --git a/src/test/regress/spec/isolation_multiuser_locking.spec b/src/test/regress/spec/isolation_multiuser_locking.spec
index 3c5193e96..8303e9459 100644
--- a/src/test/regress/spec/isolation_multiuser_locking.spec
+++ b/src/test/regress/spec/isolation_multiuser_locking.spec
@@ -1,5 +1,8 @@
 setup
 {
+	SELECT citus_internal.replace_isolation_tester_func();
+	SELECT citus_internal.refresh_isolation_tester_prepared_statement();
+
 	SET citus.shard_replication_factor TO 1;
 
 	CREATE USER test_user_1;
@@ -16,6 +19,8 @@ setup
 
 teardown
 {
+	SELECT citus_internal.restore_isolation_tester_func();
+
 	BEGIN;
 	DROP TABLE IF EXISTS test_table;
 	DROP USER test_user_1, test_user_2;
@@ -31,6 +36,7 @@ step "s1-grant"
 	SET ROLE test_user_1;
 	SELECT bool_and(success) FROM run_command_on_placements('test_table', 'GRANT ALL ON TABLE %s TO test_user_2');
 	GRANT ALL ON test_table TO test_user_2;
+	SELECT run_command_on_workers($$SET citus.enable_metadata_sync TO off; GRANT ALL ON test_table TO test_user_2;$$);
 }
 
 step "s1-begin"