diff --git a/src/backend/distributed/commands/alter_table.c b/src/backend/distributed/commands/alter_table.c
index c69332b8e..eef98cae1 100644
--- a/src/backend/distributed/commands/alter_table.c
+++ b/src/backend/distributed/commands/alter_table.c
@@ -1178,7 +1178,14 @@ ReplaceTable(Oid sourceId, Oid targetId, List *justBeforeDropCommands,
 	{
 		changeDependencyFor(RelationRelationId, sequenceOid,
 							RelationRelationId, sourceId, targetId);
-		if (ShouldSyncTableMetadata(sourceId))
+
+		/*
+		 * Skip if we cannot sync metadata for target table.
+		 * Checking only for the target table is sufficient since we will
+		 * anyway drop the source table even if it was a Citus table that
+		 * has metadata on MX workers.
+		 */
+		if (ShouldSyncTableMetadata(targetId))
 		{
 			Oid sequenceSchemaOid = get_rel_namespace(sequenceOid);
 			char *sequenceSchemaName = get_namespace_name(sequenceSchemaOid);
diff --git a/src/test/regress/expected/undistribute_table_cascade_mx.out b/src/test/regress/expected/undistribute_table_cascade_mx.out
index 150939c13..f52d3b0aa 100644
--- a/src/test/regress/expected/undistribute_table_cascade_mx.out
+++ b/src/test/regress/expected/undistribute_table_cascade_mx.out
@@ -105,5 +105,122 @@ $$);
  (localhost,57638,t,4)
 (2 rows)
 
+-- create a reference table with an implicit sequence
+CREATE TABLE reference_table_2 (id bigserial);
+SELECT create_reference_table('reference_table_2');
+ create_reference_table
+---------------------------------------------------------------------
+
+(1 row)
+
+-- this should work fine since we won't try to change sequence dependencies on mx workers
+SELECT undistribute_table('reference_table_2');
+ undistribute_table
+---------------------------------------------------------------------
+
+(1 row)
+
+create table countries(
+  id serial primary key
+  , name text
+  , code varchar(2) collate "C" unique
+);
+insert into countries(name, code) select 'country-'||i, i::text from generate_series(10,99) i;
+select create_reference_table('countries');
+ create_reference_table
+---------------------------------------------------------------------
+
+(1 row)
+
+CREATE TABLE users (
+    id bigserial
+  , org_id bigint
+  , name text
+  , created_at timestamptz default now()
+  , country_id int references countries(id)
+  , primary key (org_id, id)
+);
+SET citus.replication_model to 'streaming';
+-- "users" table was implicitly added to citus metadata when defining foreign key,
+-- so create_distributed_table would first undistribute it.
+-- Show that it works well when changing sequence dependencies on mx workers.
+select create_distributed_table('users', 'org_id');
+ create_distributed_table
+---------------------------------------------------------------------
+
+(1 row)
+
+-- count sequences that depend on "users" table's "id" column
+SELECT COUNT(*)
+FROM pg_class s
+  JOIN pg_depend d ON d.objid=s.oid AND d.classid='pg_class'::regclass AND d.refclassid='pg_class'::regclass
+  JOIN pg_class t ON t.oid=d.refobjid
+  JOIN pg_attribute a ON a.attrelid=t.oid AND a.attnum=d.refobjsubid
+WHERE s.relkind='S' AND t.relname = 'users' AND a.attname = 'id';
+ count
+---------------------------------------------------------------------
+     1
+(1 row)
+
+SELECT run_command_on_workers(
+$$
+SELECT COUNT(*)
+FROM pg_class s
+  JOIN pg_depend d ON d.objid=s.oid AND d.classid='pg_class'::regclass AND d.refclassid='pg_class'::regclass
+  JOIN pg_class t ON t.oid=d.refobjid
+  JOIN pg_attribute a ON a.attrelid=t.oid AND a.attnum=d.refobjsubid
+WHERE s.relkind='S' AND t.relname = 'users' AND a.attname = 'id';
+$$);
+ run_command_on_workers
+---------------------------------------------------------------------
+ (localhost,57637,t,1)
+ (localhost,57638,t,1)
+(2 rows)
+
+SELECT alter_distributed_table ('users', shard_count=>10);
+ alter_distributed_table
+---------------------------------------------------------------------
+
+(1 row)
+
+-- first drop the column that has a foreign key since
+-- alter_table_set_access_method doesn't support foreign keys
+ALTER TABLE users DROP country_id;
+-- set access method to columnar if pg version > 11
+DO $proc$
+BEGIN
+IF substring(current_Setting('server_version'), '\d+')::int >= 12 THEN
+  EXECUTE
+  $$
+  SELECT alter_table_set_access_method('users', 'columnar');
+  $$;
+END IF;
+END$proc$;
+SELECT COUNT(*)
+FROM pg_class s
+  JOIN pg_depend d ON d.objid=s.oid AND d.classid='pg_class'::regclass AND d.refclassid='pg_class'::regclass
+  JOIN pg_class t ON t.oid=d.refobjid
+  JOIN pg_attribute a ON a.attrelid=t.oid AND a.attnum=d.refobjsubid
+WHERE s.relkind='S' AND t.relname = 'users' AND a.attname = 'id';
+ count
+---------------------------------------------------------------------
+     1
+(1 row)
+
+SELECT run_command_on_workers(
+$$
+SELECT COUNT(*)
+FROM pg_class s
+  JOIN pg_depend d ON d.objid=s.oid AND d.classid='pg_class'::regclass AND d.refclassid='pg_class'::regclass
+  JOIN pg_class t ON t.oid=d.refobjid
+  JOIN pg_attribute a ON a.attrelid=t.oid AND a.attnum=d.refobjsubid
+WHERE s.relkind='S' AND t.relname = 'users' AND a.attname = 'id';
+$$);
+ run_command_on_workers
+---------------------------------------------------------------------
+ (localhost,57637,t,1)
+ (localhost,57638,t,1)
+(2 rows)
+
 -- cleanup at exit
 DROP SCHEMA undistribute_table_cascade_mx CASCADE;
diff --git a/src/test/regress/sql/undistribute_table_cascade_mx.sql b/src/test/regress/sql/undistribute_table_cascade_mx.sql
index dc32f106c..c8f2f82ca 100644
--- a/src/test/regress/sql/undistribute_table_cascade_mx.sql
+++ b/src/test/regress/sql/undistribute_table_cascade_mx.sql
@@ -59,5 +59,89 @@ $$
 SELECT count(*) FROM pg_catalog.pg_tables WHERE schemaname='undistribute_table_cascade_mx'
 $$);
 
+-- create a reference table with an implicit sequence
+CREATE TABLE reference_table_2 (id bigserial);
+SELECT create_reference_table('reference_table_2');
+
+-- this should work fine since we won't try to change sequence dependencies on mx workers
+SELECT undistribute_table('reference_table_2');
+
+create table countries(
+  id serial primary key
+  , name text
+  , code varchar(2) collate "C" unique
+);
+insert into countries(name, code) select 'country-'||i, i::text from generate_series(10,99) i;
+select create_reference_table('countries');
+
+CREATE TABLE users (
+    id bigserial
+  , org_id bigint
+  , name text
+  , created_at timestamptz default now()
+  , country_id int references countries(id)
+  , primary key (org_id, id)
+);
+
+SET citus.replication_model to 'streaming';
+
+-- "users" table was implicitly added to citus metadata when defining foreign key,
+-- so create_distributed_table would first undistribute it.
+-- Show that it works well when changing sequence dependencies on mx workers.
+select create_distributed_table('users', 'org_id');
+
+-- count sequences that depend on "users" table's "id" column
+SELECT COUNT(*)
+FROM pg_class s
+  JOIN pg_depend d ON d.objid=s.oid AND d.classid='pg_class'::regclass AND d.refclassid='pg_class'::regclass
+  JOIN pg_class t ON t.oid=d.refobjid
+  JOIN pg_attribute a ON a.attrelid=t.oid AND a.attnum=d.refobjsubid
+WHERE s.relkind='S' AND t.relname = 'users' AND a.attname = 'id';
+
+SELECT run_command_on_workers(
+$$
+SELECT COUNT(*)
+FROM pg_class s
+  JOIN pg_depend d ON d.objid=s.oid AND d.classid='pg_class'::regclass AND d.refclassid='pg_class'::regclass
+  JOIN pg_class t ON t.oid=d.refobjid
+  JOIN pg_attribute a ON a.attrelid=t.oid AND a.attnum=d.refobjsubid
+WHERE s.relkind='S' AND t.relname = 'users' AND a.attname = 'id';
+$$);
+
+SELECT alter_distributed_table ('users', shard_count=>10);
+
+-- first drop the column that has a foreign key since
+-- alter_table_set_access_method doesn't support foreign keys
+ALTER TABLE users DROP country_id;
+
+-- set access method to columnar if pg version > 11
+DO $proc$
+BEGIN
+IF substring(current_Setting('server_version'), '\d+')::int >= 12 THEN
+  EXECUTE
+  $$
+  SELECT alter_table_set_access_method('users', 'columnar');
+  $$;
+END IF;
+END$proc$;
+
+SELECT COUNT(*)
+FROM pg_class s
+  JOIN pg_depend d ON d.objid=s.oid AND d.classid='pg_class'::regclass AND d.refclassid='pg_class'::regclass
+  JOIN pg_class t ON t.oid=d.refobjid
+  JOIN pg_attribute a ON a.attrelid=t.oid AND a.attnum=d.refobjsubid
+WHERE s.relkind='S' AND t.relname = 'users' AND a.attname = 'id';
+
+SELECT run_command_on_workers(
+$$
+SELECT COUNT(*)
+FROM pg_class s
+  JOIN pg_depend d ON d.objid=s.oid AND d.classid='pg_class'::regclass AND d.refclassid='pg_class'::regclass
+  JOIN pg_class t ON t.oid=d.refobjid
+  JOIN pg_attribute a ON a.attrelid=t.oid AND a.attnum=d.refobjsubid
+WHERE s.relkind='S' AND t.relname = 'users' AND a.attname = 'id';
+$$);
+
+
 -- cleanup at exit
 DROP SCHEMA undistribute_table_cascade_mx CASCADE;